N-acetyl muramic acid

N-acetyl muramic acid
Sugar unit of bacterial peptidoglycan, consisting of N-acetyl glucosamine bearing an ether-linked lactyl residue on carbon 3. Repeating unit of the cell wall polysaccharide is N-acetyl muramic acid linked to N-acetyl glucosamine via a b(1-4)-glycosidic bond, that can be cleaved by lysozyme.

Dictionary of molecular biology. 2004.

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  • muramic acid — 2 Amino 3 O (1 carboxyethyl) 2 deoxy d glucose; d glucosamine and lactate in ether linkage between the 3 and 2 positions, respectively; a constituent of the mureins in bacterial cell walls. * * * mu·ram·ic acid myu̇ .ram ik n an amino sugar… …   Medical dictionary

  • bacteria — bacterial, adj. bacterially, adv. /bak tear ee euh/, n.pl., sing. bacterium / tear ee euhm/. ubiquitous one celled organisms, spherical, spiral, or rod shaped and appearing singly or in chains, comprising the Schizomycota, a phylum of the kingdom …   Universalium

  • Penicillin binding proteins — (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constitutent of many bacteria; the name just reflects the way by which the protein was discovered. All beta lactam… …   Wikipedia

  • lysozyme — Glycosidase that hydrolyzes the bond between N acetyl muramic acid and N acetyl glucosamine, thus cleaving an important polymer of the cell wall of many bacteria. Present in tears, saliva, and in the lysosomes of phagocytic cells, it is an… …   Dictionary of molecular biology

  • murein — Cross linked peptidoglycan complex from the inner cell wall of all Eubacteria. Constitutes 50% of the cell wall in Gram negative and 10% in Gram positive organisms, and comprises b (1 4) linked N acetyl glucosamine and N acetyl muramic acid… …   Dictionary of molecular biology

  • peptidoglycan — (= murein) Cross linked polysaccharide peptide complex of indefinite size found in the inner cell wall of all bacteria (50% of the wall in Gram negative, 10% in Gram positive). Consists of chains of approximately 20 residues of b (1 4) linked N… …   Dictionary of molecular biology

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